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2023 Startups to Watch: Resilient Lifescience


thumbnail Brad Charlie
From left: Resilient Lifescience Co-Founders Brad Holden, CEO, and Charlie Proctor, CTO.
Resilient Lifescience

This is one of Pittsburgh Inno's 10 Startups to Watch in 2023. These budding enterprises have been selected following suggestions made by experts in the startup community and an evaluation by editorial staff at Pittsburgh Inno and the Pittsburgh Business Times. A list of all 10 Startups to Watch in 2023 is now available to read online.


Resilient Lifescience Inc.

About the company: Resilient Lifescience Inc. is developing a wearable medical device that can detect and reverse an opioid overdose. The wearable device detects an overdose through its sensors and can then automatically administer naloxone to the wearer, removing the need for a bystander to be present in order to save someone from an overdose. Founded in 2022 by CEO Brad Holden and CTO Charlie Proctor, the North Side-based company has raised $820,000 in funding, including a $500,000 investment from the Richard King Mellon Foundation as a result of its first-place finish in the philanthropic organization’s second annual Social-Impact Pitch Competition. Resilient’s two co-founders are its only full-time employees for now.

Why we’re watching: With opioid-related deaths on the rise over the past decade, the need for innovative solutions that address the crisis remain pressing. Resilient Lifescience’s wearable device has the potential to save countless lives given its ability to automatically detect and administer naloxone, which will likely make it a novel victor in the fight against opioid overdose deaths. The company is in the process of raising a $1.5 million seed round, which will enable it to take the early forms of the device from proof-of-concept to production-ready and to execute early trials to demonstrate its effectiveness.

What’s their vision for 2023: “Our vision is that by the end of 2023, we’ll be on a clear path to FDA approval,” Holden said. “We’ll have built out our sensing device, demonstrated its effectiveness in early trials, and have laid the foundation for our regulatory approval and commercialization.”


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